Blimp-1 could help 2ME2 induce differentiation on myeloma cell lines by downregulating pax-5 mRNA and upregulating xbp-1 mRNA.

 
  • Blimp-1可通过抑制pax-5 mRNA表达水平,从而提升xbp-1mRNA表达水平,促进骨髓瘤细胞分化。
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