Biphenylacetic acid was synthesized from biphenyl by chloromethylation, cyanation and hydrolysis with 55% sulfuric acid in an overall yield of 72%.

• 以联苯为原料,经氯甲基化、氰基取代及酸水解制得4-联苯乙酸,并优化了各步反应条件,新工艺总收率72%25。