Biophysical function of the mutations was categorized according to dominant-negative (>50%) or haploinsufficiency (50%) reduction in cardiac repolarizing IKs potassium channel current.

 
  • 基因变异的生物物理功能的分类是依据显性遗传((>50%25)或者心脏除极过程中慢性钾离子电流钾通道的状态单倍剂量不足减少(50%25)。
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