Based on the property of bacterial endotoxin,the effects of affinity chromatography,ion exchange chromatography and hydrophobic interaction chromatography on removal of endotoxin in the pu- rification of recombinant12 5Ser- IL - 2 were compared.

• 针对细菌内毒素的化学性质 ,比较了用亲和层析法、离子交换层析法和疏水相互作用层析法等 3种层析法去除基因重组 1 2 5Ser- IL- 2产品中细菌内毒素的效果。