Background: Adenosine deaminase (ADA) is an important enzyme of purine nucleotides catabolism. It specially catalyzes the unreversible deamination of adenine nucleoside to inosine. The inosine is then oxidized to uric acid.

• 研究背景：腺苷脱氨酶(Adenosine deaminase，ADA)是一种核酸分解代谢关键酶，可特异性催化腺嘌呤核苷产生不可逆脱氨反应，生成次黄嘌呤，最终氧化成尿酸排出体外。