BAFF is a critical survival/maturation factor for peripheral B cells and this activity is mediated through a BAFF-specific receptor,BAFF-R.

• BAFF是外周血B细胞一个关键的存活与成熟因子,它的活性通过其特异性受体BAFF-R调节,其过表达与自身免疫性疾病发生和B细胞肿瘤形成有关。