BACKGROUND: Endotoxin(ETx) was associate with acute lung injury, It has been hypothesized that ETx may have a role in the pathogenesis of chronic obstructive pulmonary disease (COPD) and blood stasis syndrome(BSS) .

• 为研究内毒素(ETx)在慢性阻塞性肺疾病(COPD)发病机制中的作用、ETx和内皮素(ET-1)与COPD肺血瘀证发生和发展的关系以及中药益气活血注射剂黄芪、川芎嗪对肺血瘀证的影响而设计本研究。