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- The binding between these ligands and receptors promotes the adhesion of cells.Polyethyleneglycol (PEG) can resist cell adhesion. 聚乙二醇(PEG)可以抵抗细胞在表面的黏附,我们利用含有PEG的表面小分子来调节细胞黏附。
- Conclusion A multidrug resistance cell line (SPC-A-1/CDDP) from human lung adenocarcinoma is established.It can be used to downstream experiment. 结论本研究建立了稳定的人肺腺癌多药耐药细胞系(SPC-A-1/CDDP),可应用于下游实验。
- AIM and METHODS: Matrine (50mg/L) potentiated the cytotoxicity of daunorubicin (DNR) in human leukemia multidrug resistance cell line K562/A02 by MTT assay. 方法和结果:经MTT法发现苦参碱50mg/L能增加K562/A02对柔红霉素的敏感性,使柔红霉素半数抑制浓度(IC50)由14?92mg/L降至8?29mg/L,部分逆转了K562/A02对柔红霉素耐药性,逆转倍数为1?80倍。
- Bromodeoxyuridine resistant cells are obtained by a similar procedure. 用同样的处理方法,得到溴脱氧尿甙抗性细胞。
- Objective:To study the effects of oridonin on inducing the multi-drug resistant cell line K562/A02 to apoptosis and reversing their multi-drug resistance. 目的:探讨冬凌草甲素诱导多药耐药细胞系K562/A02凋亡、逆转耐药性的作用。
- Presumably poliovirus was incorporated into the resistant cells during the fusion process. 据推测,脊髓灰质炎病毒是在融合过程中渗入到耐受细胞内的。
- Tetrandrine, neferine and dauricine showed obvious potenitiation of vincristine induced apoptosis in the human mammary MCF 7 multidrug resistant cells. 粉防己碱、甲基莲心碱和蝙蝠葛碱均有明显的增强长春新碱诱导人乳腺癌MCF 7多药耐药细胞的凋亡作用
- Methods Human myeloid leukemia cells, K562 and NB4, were transduced by MDR retrovirus and the resistant cells were selected. 方法用MDR病毒转导人类白血病细胞K562和NB4,获得耐药细胞系;
- A drug or preparation containing arsenic. 砷化合物含砷的药剂或制剂
- His wife poisoned him with arsenic. 他妻子用砒霜把他毒死了。
- Vincristine could affect the activity of p38 MAPK in gastric cancer cell SGC7901 and multidrug resistant cell SGC7901/VCR. p38MAPK信号转导途径可能与长春新碱的抗肿瘤活性相关 ,肿瘤细胞内 p38MAPK对长春新碱刺激的反应速度可能与胃癌长春新碱耐药相关
- Objective To study drug resistant mechanism and reversal of glioma we established C 6 MDR drug resistant cell line(C 6/adr). 目的 为研究脑胶质瘤的耐药、机理及逆转 ,建立了C6耐阿霉素细胞株 (C6/adr)MDR细胞系。
- Construction of the Arsenic Resistance Plasmids and the Conjugative Transfer to Thiobacillus caldus 抗砷载体的构建及在喜温硫杆菌中的接合转移
- The effects of saponins Rb1 on the intracellular concentration of DNR in human leukemic multi-drug resistant cell K562/HHT in vitro. 人参皂甙单体Rb1对多药耐药细胞系K562/HHT细胞内柔红霉素浓度的影响
- Methods A resistant cell line-HT29/L-OHP was established by gradually increasing the dose of L-OHP and intermittent administration. 方法 采用逐步递增L-OHP浓度,间歇作用体外诱导法培养建立了人结肠癌L-OHP 耐药细胞模型HT29/L-OHP。
- Her resistance to the proposal has crumpled. 她对这个建议的抵触情绪已化为乌有了。
- Objective: To study the possible difference in genomic DNA between human ovarian carcinoma cisplatin- resistant cell COC1/DDP and sensitive cell COC1 and the possible significance during development of ovarian carcinoma resistance to cisplatin . 目的:探讨人卵巢癌顺铂耐药细胞株COC1/DDP及其药物敏感细胞株COC1在基因组DNA水平上可能存在的差异,以及这种差异在肿瘤耐药性产生中的意义。
- Keywords Arsenic resistance gene;Acidithiobacillus caldus;Conjugative transfer;Extremely acidophilic chemolithotrophic bacteria; 关键词抗砷基因;喜温硫杆菌;接合转移;极端嗜酸性自养细菌;
- The analysis showed a few grains of arsenic in the solution. 分析显示溶液中有几格令的砷。
- Objective To explore the effects of saponins Rb1 on the intracellular concentration of DNR in human leukemic multi-drug resistant cell K562/HHT in vitro. 目的 探讨中药钙离子通道拮抗剂人参皂甙单体Rb1对白血病多药耐药细胞系 (K562 /HHT)细胞内柔红霉素浓度的影响。