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- Aromatase inhibitors, such as aminoglutethimide and anastrozole, work in a different way to lower estrogen leels. 氨鲁米特和阿那曲唑作为芳香酶抑制剂是通过另一途径来降低雌激素。
- The musculoskeletal complaints common to aromatase inhibitors can be addressed with NSAID pain relievers. 芳香酶抑制剂常见的肌和骨骼的主诉能够通过非甾体抗炎药来处理。
- Unlike tamoxifen, aromatase inhibitors do not cause menopausal symptoms, but they may increase risk of osteoporosis. 与三苯氧胺不同的是,芳香抑制剂不会引起绝经期症状,但可增加骨质疏松症危险。
- Several large-scale clinical trials about aromatase inhibitors and medical ovarian ablation are ongoing and attract attention widely. 芳香化酶抑制剂及药物去势等多个大型的临床研究还正在进行并备受关注。
- The results of ongoing studies "should inform us whether bisphosphonates can be used to preent bone loss due to aromatase inhibitors," he added. 他还补充说,目前研究尚未结束,其最终结果“将会告诉我们二膦酸盐类药物是否能够用于预防芳香酶抑制剂引起的骨盐丢失。”
- Aromatase inhibitors are superior to tamoxifen in postmenopausal patients, and preclinical data suggest that zoledronic acid has antitumor properties. 芳香酶抑制剂在绝经后患者中优于他莫昔芬,且临床前数据表明唑来膦酸具有抗肿瘤特性。
- Aromatase inhibitors (anastrozole, exemestane, letrozole) block peripheral production of estrogen in postmenopausal women. 芳香酶抑制剂(阿那曲唑、依西美坦、来曲唑)阻断绝经后妇女周围雌激素的产生。
- Concern has been raised that phytoestrogens may interfere with selective estrogen receptor modulators and aromatase inhibitors. 植物性雌激素可能和选择性的雌激素受体调节剂及芳香酶抑制剂相互作用,从而引起人们的关注。
- The third-gene ration aromatase inhibitors have become one of the first-line therapies of post menopausal breast cancer. 第3代芳香化酶抑制剂已成为绝经后乳腺癌的一线药物选择之一。
- OBJECTIVE: To summarize the aspect of clinical evaluation and progresson aromatase inhibitors for the treatment of breast cancer. 目的:介绍芳香化酶抑制剂的研究进展,评价其在乳腺癌治疗中的应用及临床价值。
- Now, tamoxifen is still the standard endocrine therapeutic drug or the premenopausal patients, but aromatase inhibitors can bring more benefit for the postmenopausal patients. 目前,三苯氧胺对绝经前患者仍是内分泌治疗的标准用药,但对绝经后患者应用芳香化酶抑制剂会有更大的效益。
- The musculoskeletal complaints common to aromatase inhibitors can be addressed with NSAID pain relieers. aginal dryness can be ameliorated with oer-the-counter remedies. 芳香酶抑制剂常见的肌和骨骼的主诉能够通过非甾体抗炎药来处理。阴道干燥能够通过非处方药物治疗改善。
- As the third generation of aromatase inhibitor,letrozole has been used widely in the sphere of tumor. 来曲唑作为第3代芳香酶抑制剂,已被广泛应用于肿瘤领域。
- BMD should be measured in women with chemotherapy-induced ovarian failure and particularly in patients taking aromatase inhibitors (eg, anastrozole, letrozole) (Table 3). 在治疗导致卵巢功能衰竭的妇女和使用芳香酶抑制剂(如阿纳托唑、来曲唑)的患者,骨矿物质密度需要测量。
- Now, tamoxifen is still the standard endocrine therapeutic drug for the premenopausal patients, but aromatase inhibitors can bring more benefit for the postmenopausal patients. 目前,三苯氧胺对绝经前患者仍是内分泌治疗的标准用药,但对绝经后患者应用芳香化酶抑制剂会有更大的效益。
- RESULTS &CONCLUSION: Position of Aromatase inhibitors for the treatment of late breast cancer and postoperative adjuvant treatment of early breast cancer is made certain. 结果与结论:芳香化酶抑制剂用于绝经后晚期乳腺癌和早期乳腺癌术后辅助治疗的地位已经确立。
- Objective:To compare the difference between conventional drug abortion protocol and the same protocol combined with aromatase inhibitor. 目的:比较常规药物流产方案配伍芳香化酶抑制剂与常规药物流产方案的差异性。
- This study was designed to induce sex-reversed male phenotype chickens with letrozole, an aromatase inhibitor, and dihydrotesterone. 本论文用来曲唑、二氢睾酮、来曲唑与二氢睾酮联合处理性别分化前的鸡胚胎,观察对鸡性别分化的影响,探索低剂量来曲唑诱导雄性表型性反转鸡的可行性,探讨二氢睾酮及其与低剂量来曲唑联合处理鸡胚诱导雄性表型性反转鸡的效果,为禽类的性别控制提供参考数据。
- Steroidal aromatase inhibitor can inhibit the aromatase activity, interdict the reaction, and inhibit the estrogen formation, so that it can cure the breast cancer. 甾体芳香酶抑制剂能抑制芳香酶活性,阻断芳构化反应,抑制雌激素生成,从而达到治疗乳腺癌的目的。
- An NCI committee reiewing the study came down against the trial, because of its high cost and because two large studies comparing aromatase inhibitors against placebo are already under way. 一位国立癌症研究所委员对这项研究进行评估反对这项试验,因为其带来高成本并且由于两项大宗比较芳香酶抑制剂和安慰剂的研究正在进行。