Approximately 50% or more of the high-potency bisphosphonates is bound to hydroxyapatite on exposed bone mineral surfaces undergoing resorption.

• 大约有50%25的双磷酸盐必然被暴露在骨表面的羟磷酸盐重吸收。剩余的双磷酸盐被肾脏排泄；