Apart from its effect on the pituitary,it has been suggested that CRH acts within the central nervous system(CNS) and influence a number of behavioral,neuroendocrine,and autonomic responses to stress.

• CRH除对垂体腺的影响外，在中枢神经系统（central nervous system ，CNS）中CRH可影响应激导致的行为、神经内分泌、自发反应等。