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- It is a hotspot for tumor treatment research to look for safe and effective antitumor drugs from traditional Chinese herbal medicine. 摘要从传统的中草药这些天然物质中寻找安全有效的抗肿瘤药物是目前肿瘤治疗研究的一个热点。
- Antitumor drug vinorelbine tartrate was synthesised from vinblastine sulfate in 15. 从硫酸长春碱合成抗癌药酒石酸长春瑞宾，总收率15．3%25。
- It is reported that DNA topoisomerase has a high expression level, which related with the mechanism of many antitumor drugs. 研究发现,拓扑异构酶在肿瘤组织中高表达,许多抗肿瘤药物的作用机制与抑制拓扑异构酶有关。
- Purpose To synthesize a new antitumor drug 2-methoxyestradiol which is an angiogenesis inhibitor. 目的合成抗肿瘤新药新生血管形成抑制剂2甲氧基雌二醇。
- This review provides the delivery mechanism of FR-mediated antitumor drugs and highlights the novel folate-drug conjugates and their activities. 本文对叶酸受体介导的抗肿瘤药物的作用机制进行综述,介绍近几年研究者设计并合成的叶酸-药物缀合物及其活性测试的结果。
- The study about the polymer carriers for antitumor drugs trends to search a drug carrier material that is more selective and effective. 抗肿瘤药物高分子载体的研究重点目前在于寻找选择性更强、疗效更好的载药材料。
- Objective To study the antitumor effect of novobiocin(NOVO) on patients primary liver cancer cells, and the modulation of NOVO on some clinical antitumor drugs. 目的研究新生霉素(NOVO)对人肝癌细胞的抗癌及其对临床常用抗癌药的调节作用。
- As a newly developed non-classic folate antitumor drug, nolatrexed dihydrochloride (NLTX),is a hymidylate synthase(TS) inhibitor. 盐酸洛拉曲克(NLTX)为胸苷合成酶特异性抑制剂，为新合成的抗肿瘤药物。
- OBJECTIVE: To testify the relationship between the P53 gene status and chemosensitivity and explore the mechanism of antitumor drug"s resistance. 目的：研究P53基因状况与抗癌化疗敏感性的关系，对抗癌药耐药机制进行探讨。
- McAb 3A5, a rat monoclonal antibody, was linked to norcantharidin (NCTD),an antitumor drug currently in clinical use, by active ester method. 用大鼠单克隆抗体3A5与去甲斑蝥素（NCTD）制备偶联物。
- OBJECTIVE: To summarize the prevention and management of ADRs induced by antitumor drugs to provide references for their rational administration in the clinic. 目的:对抗肿瘤药所致的不良反应及其防治进行归纳总结,以期为临床合理用药提供参考。
- This article reports the experiment studies on treating the S 180 sarcomas of KM mice with high intensity electric pulse and antitumor drug (cyclophosphamide). 报道了用强电脉冲结合抗癌药物环磷酰胺作用于昆明小鼠S-180肉瘤。
- CONCLUSION DDP resistant L1210 subline is a good experimental model in vitro for the study of mechanism of antitumor-drug resistance and the screening of antitumor drug. 结论DDP耐药性L1210细胞亚系的建立，为深入研究肿瘤细胞耐药机制、寻找逆转耐药的措施提供了较好的体外实验模型。
- Objective To compare the diverse effects of three kinds of antitumor drugs [Camptothecin (CAM),Amsacrine (AMSA),Vinblastine (VIN)] on the cell cycle of lymphocytic cell line (Molt 4) or human promyelocytic cell line (HL 60). 目的 比较 3种不同的抗肿瘤药物 (喜树碱、胺苯吖啶、长春花碱 )对培养的淋巴细胞性 (Molt 4)或髓样白血病细胞 (HL 60 )的细胞周期的影响。
- Objective: To examine the effects of green tea catechins (GTC) with antitumor drugs such as adriamycin(ADM), 5-fluorouracil(5-Fu) and cytarabine(Arac) on the growth inhibition of BEL-7402 and SMMC-7721 human hepatocarcinoma cell lines. 目的 :研究绿茶儿茶素 (GTC)与抗癌药阿霉素 (ADM)、5 -氟尿嘧啶 (5 -Fu)和阿糖胞苷 (AraC)联合应用对人肝癌细胞体外生长的抑制作用。
- The most common therapeutic drugs involved were antitumor drugs and hormones. 36 kinds of single drug resulted in ADRs 316 times. The ADRs times of Ara C was the highest (138 times),the second was Prednisone. 引起ADRs的药物以抗肿瘤药最多，其次为激素类：引起ADRs的单种药共36种（316例次），其中阿糖胞苷居首（138例次），其次为强的松；
- The results suggest that it is possible to produce podophyllotoxin quickly by tissue culture, and provide much raw material to antitumor drugs with little damage to the natural resources. 通过组织培养可在不破坏自然资源的前提下快速生产鬼臼毒素，从而为开发鬼臼毒素类抗癌药物提供大量原料。
- METHO-DS:The pharmacoeconomic research papers on antitumor drugs published in domestic academic magazines over the 10 years ever since 1995 were evaluated by tabulating of the items. 方法:收集1995年以来国内学术期刊发表的有关肿瘤药物经济学论文,并对文献内容分项列表进行评估。
- A rat monoclonal antibody was linked to norcantharidin (NCTD), an antitumor drug currently in clinical use McAb 3A5. The 3A5 NCTD conjugate retained complete immunoreactivity of McAb 3A5 to human hepatoma cancer BEL 7402 cells. 用单抗3A5制备与去甲斑蝥素（NCTD）的偶联物。 ELISA检测结果表明：3A5?NCTD偶联物保持对人肝癌BEL?7402细胞的免疫反应性。
- Research result showed that the anticancer mechanisms of allicin were oxidation resistance, inhibiting the form of carcinogens, inducing tumor cello apoptosis, improving cellular immune function and enhancing radiosensitizing effect of antitumor drug. 目前的研究结果显示，大蒜素的抑癌机制为：抗氧化，抑制致癌物的形成，影响肿瘤细胞的细胞周期并诱导肿瘤细胞调亡，增强机体免疫功能，对抗肿瘤药物有增敏作用等。
