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- I focus on the role of antisense RNAs in plasmid replication. 本文着重叙述反义RNA在质粒复制中的作用及其进展。
- Applying antisense oligonucleotide to block the expression of CLC-3 mRNA. 应用反义核酸的阻断CLC一3 mRNA在细胞中的表达。
- Objective:In order to explore the effects of CD40 antisense RNA on Balm cell. 目的：探讨CD40反义RNA对Balm细胞的影响。
- Meanwhile, the application of antisense gene technology is prospected. 并对反义基因技术的应用进行了展望。
- Cyclin D3 antisense oligodeoxynucleotides were used in in vitro culture study. 用反义技术和流式细胞术研究周期蛋白D3在白血病细胞增殖中的作用。
- However, the molecular mechanism of this antisense regulation remains unknown. 然而这种反义调节的分子机理还不甚明了。
- When sense and antisense RNA molecules meet, they bind to each other and form double-stranded RNA. 当感觉和抗感觉RNA分子相遇的时候，他们结合在一起形成双链的RNA。
- VES had no effects on p38 and ATF-2. Antisense to ATF-2 oligomers also had no effect on VES-mediated apoptotic rate. VES 并不改变p38 蛋白的表达,且其下游转录因子ATF-2 的表达未发生改变,转染ATF-2反义寡聚核苷酸后VES 诱导的细胞凋亡亦未发生改变。
- Antisense IRAK 2 ODN blocked IRAK 2 mRNA translation and protein expression was inhibited. 反义IRAK 2寡核苷酸可阻断IRAK 2mRNA的翻译 ,从而抑制IRAK 2蛋白的表达 ,抑制率达45%25 ;
- Antisense oligonucleotide (4 ug/mL) can decrease the content of CLC-3 mRNA and make no influence on cell cycle. ASO(4林留mL)可以减少细胞CLC一3 mRNA的含量，不
- Apoptosis of drug-resistant human ovarian cancer cell line COC_1/DDP induced by survivin antisense oligonucleotides. Survivin反义寡核苷酸诱导人卵巢癌耐药细胞株COC_1/DDP凋亡的实验研究
- Objective To construct the antisense expression vector of human Na + H + exchanger 1 (NHE 1). 目的 构建人Na+ H+ 交换蛋白 1(Na+ H+ exchanger 1,NHE 1)基因反义真核表达载体。
- Objective To explore the effect of VEGF antisense on sensitivity of AML and CML cells to Daunorubicin (DNR). 目的 探讨血管内皮生长因子VEGF(VascularEndothelialGrowthFactor)反义核酸与柔红霉素联用 ,对AML、CML细胞药物敏感性的影响。
- The proliferation of GLC-82, NCI-H446 and NCI-H460 cells were inhibited by antisense Slp2 gene conspicuously. 转染Slp2反义基因后的肺癌细胞系GLC-82、NCI-H446、NCI-H460的细胞生长速度明显减慢;
- Objective To study antiviral effect of Lihposome-mediated antisense oligonucleotides COS-ASIN. 目的 研究脂质体介导的反义寡核苷酸在体外对乙型肝炎病毒基因复制和表达的抑制。
- The recombinant plasmid of antisense TIMP 1 has a certain extent reverse effects on liver fibrosis. 反义TIMP 1表达质粒对肝纤维化有一定的逆转作用
- Conclusion ECE-1 expression in 16HBE cells can be inhibited by ECE-1 antisense RNA in vitro. 而Westerbloting亦显示anti -16HBE细胞ECE表达量比 16HBE细胞明显低。 结论 ECE反义RNA表达载体可抑制人气道上皮细胞ECE -1表达与分泌
- The sequencing result of antisense DNA fragment was in accordance with the known LMP1 gene. 结果 :酶切产物和PCR产物的凝胶电泳显示 4 0 0bp左右的目的基因片段 ,测序结果显示与已知LMP1基因序列一致。
- Objective To observe the effect of telomerase antisense oligodexynucleotides on human gastric cancerous cell line. 目的:观察端粒酶反义寡聚脱氧核苷酸对人胃癌细胞株的作用。
- After A549 was infected by recombinant retroviral vector expressing antisense ANG,ANG protein level decreased greatly. 构建出含反义血管生成素的逆转录病毒载体 ,感染A5 4 9细胞后 ,能有效抑制A5 4 9细胞血管生成素蛋白的表达。
