Anti HBs in mice sera was positive 1 week after plasmid injection. The level of antibody peaked 4 weeks later, and high titer was kept for at least 8 weeks;

• 注射基因疫苗 1周后 ,血清中抗 HBs抗体转阳 ,4周后抗体达到高峰 ,并以高水平维持至少 8周 ;