Animals were killed at day 3,7,14and 28 after BLM administration. The total RNA was extracted from the lung tissue. The expressions of SPsmRNA were analyzed with Northern blot.

• 方法气管内灌注博莱霉素A5，复制肺纤维化模型，分别于3、7、14和28天处死动物，提取肺组织总RNA，进行Northern杂交。