Animal experiment and clinical research show ,reactive oxygen species plays an important role in cerebral ischemia reperfusion,p47~(phox) is associated with ischemia reperfusion injury from p47~(phox) function in ROS generation.

• 动物实验和临床研究表明，活性氧在脑缺血再灌注中发挥了重要作用，从NAD(P)H氧化酶p47~(phox)在ROS的产生过程中的发挥重要作用可知，p47~(phox)与脑缺血再灌注损伤密切相关。