And there was statistical difference.Conclusion: Used as adjuvant therapy of periodontitis, minocycline hydrochloride ointment can improve clinical indexes of periodontitis effectively.

• 结论：盐酸二甲胺四环素牙科软膏缓释剂作为牙周炎的辅助治疗，能有效改善牙周炎的临床各项观察指标。