Analgesia caused by ip baclofen 6. 4 a. nd 12. 8 mg/kg was examined by the hot plate method, showing no accompanied significant changes in 5-HT and 5-HIAA in mouse brains.

• 小鼠在ip氯苯氨丁酸(baclofen)6.；4mg/kg出现镇痛效应时；脑内5-HT及5-HIAA均无明显增多。