An increasing number of experimental and clinical studies suggests that many of the pleiotropic effects of statins may be attributable to the inhibition of small GTP-binding proteins.

• 他汀类药物具有调脂以外的心血管保护作用,越来越多的实验和临床研究显示,他汀类药物的多效性很大程度上和其抑制小G蛋白的活性有关。