Among the three step (Z-disc split, degradation of damaged protein, protein synthesization )of DOMS, degradation of damaged protein through Ubiquitin-Proteasome Pathway (UPP) is the step that limit the progress rate of DOMS.

• 在DOMS经历的Z带撕裂、损伤蛋白质降解和蛋白质合成三个主要阶段中,损伤蛋白质的泛素-蛋白酶体特异性蛋白质降解途径(UPP)降解是主要的限速过程,而对损伤蛋白质UPP降解贡献最大的是糖皮质激素(GC)通路的激活。