Aminoglycoside antibiotics are candidate drugs for a large number of such genetic diseases; however, aminoglycosides are toxic, lack specificity and show low efficacy in this application.

• 氨基糖苷类抗生素是治疗大部分此类遗传病的手段；但是，目前使用的氨基糖苷具有毒性，缺乏特异性并且使用效率低。