All of four aromatic amines inhibited acetylation of isoniazid, but amides did not. 4-Aminobenzoic acid can be considered as a combined-drug for increasing and prolonging the blood level of isoniazid.

• 四种芳香胺都具有抑制乙酰化代谢的作用,而酰胺类没有这种作用,并提出对氨基苯甲酸可考虑作为合并药物以提高异烟肼的血水平和持续时间。