Akt is one of the critical mediators in cellular signaling, and overactivation of Akt and its related pathway are associated with the initiation and progression of many malignant tumors.

• Akt是细胞信号转导途径中的关键调控因子，其自身及相关信号通路的过度活化已被证实与多种恶性肿瘤的发生和进展密切相关。