After renal ischemia reperfusion, the high expression of iNOSmRNA in tubules is an important molecular mechanism of renal ischemia reperfusion injury (2) Keep cNOS/iNOS constant may be important for mudulation of renal blood flow and GFR.

• 缺血再灌注后 ,皮质肾小管上皮中iNOSmRNA的高表达是导致肾缺血再灌注损伤的重要分子机制。 (2 )cNOS/iN OS比值与缺血再灌注过程中肾功能的变化密切相关 ,该比值的恒定对肾血流量和肾小球滤过率(GFR)的调节可能具有重要意义