After 4 weeks of dietary manipulation,the DFM was intraperitoneally injected with low dose of streptozotocin(STZ)(35mg/kg) to induce type 2 diabetic model.

• DFM组采用高糖高脂喂养加低剂量链脲佐菌素(35mg/kg)注射建立2型糖尿病模型。