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- Activation of hepatic stellate cell (HSC) has become the cellular basis for hepaticfibrogenesis. 肝星状细胞(HSC)的活化是肝纤维化发生、发展的细胞学基础。
- It is well known that the activation of hepatic stellate cells (HSCs) is the key event in the process of hepatic fibrosis. 肝星状细胞(hepatic stellate cells,HSCs)的活化被认为是这一过程中的关键事件。
- In this article, we reviewed the research advancement in the signal transduction pathway of nuclear receptor and membrane receptor during the activation of hepatic stellate cells. 本文就肝星状细胞激活过程中一些重要的膜受体、核受体信号转导途径及其研究进展作一综述。
- XBR can prevent the occurrence and development of hepatic fibrosis in rats,the effect may be related to its preventing liver cell against injury,inhibiting the synthesis of extracellular matrix(ECM) and the activation of hepatic stellate cell(HSC). 消瘢方能有效预防肝纤维化的发生、发展,其作用可能与保护肝细胞,抑制细胞外基质合成及HSC活化有关。
- Effects of estrogen on the activation of hepatic stellate cells and collagen synthesis in liver fibrotic rats 雌激素对肝纤维化大鼠肝星状细胞活化及胶原合成的影响
- Relationship between somatostatin receptors and activation of hepatic stellate cell 生长抑素受体与肝星状细胞活化的相关性研究
- The inhibition effect of oxvmatrine on the activation of paracrine pathway of hepatic stellate cells 氧化苦参碱对大鼠肝星状细胞旁分泌活化途径的抑制作用
- Effects of Scutellaria baicalensis stem-leaf total flavonoid on the Activation of Hepatic Stellate Cells 黄芩茎叶总黄酮对纤维化大鼠肝脏星形细胞活化的影响
- INFLUENCE OF BAOGANLEIFUFANG ON ACTIVATION OF HEPATIC STELLATE CELL AND EXPRESSION OF ECM 保肝类中药复方对肝星形细胞活化及细胞外基质表达的影响
- Relationship between the activation of hepatic stellate cell and the early stage of liver fibrosis in experimental diabetic tree shrews 肝星状细胞激活与糖尿病树鼩早期肝纤维化的关系
- Activation of hepatic stellate cells in a cirrhotic rat liver transplantation model using small-for-size grafts: The significance of Rho-ROCK signaling pathway 肝星状细胞的激活和Rho-ROCK信号通路在纤维化大鼠小肝移植中的作用
- Activation of hepatic stellate 星状细胞活化
- Objective:To study the effects of bupleurum on collagen degradation of hepatic stellate cell in vitro. 目的:观察柴胡对肝星形细胞有关胶原降解基因表达的影响。
- Recently, a lot of data indicate hepatic stellate cells (HSC) is the key cell of formation of ECM and HSC is also the core link of occurrenc of hepatic fibrosis. 现已证实,肝星形细胞(hepatic stellate cell,HSC)是肝脏产生 ECM 的主要细胞,HSC 活化是肝纤维化发生的中心环节。
- AIM: To investigate the effect of Baoganning (BGN) on the proliferation of hepatic stellate cells (HSCs) stimulated by leptin and its relevant mechanisms. 目的:观察中药复方保肝宁对瘦素刺激的肝星状细胞(Hepatic stellate cells,HSCs)增殖功能的影响及其发生的可能机制。
- Conclusion: Inhibition of hepatic stellate cell proliferation and collagen synthesi s may be one important mechanism of hepatoprotective and antifibrotic properties of silibinin. 结论:抑制贮脂细胞增殖和胶原合成可能是水飞蓟宾保护肝脏抗硬化机制之一。
- Aim To investigate the role of nuclear factor-KB (NF-KB) inhibitor caffeic acid phenethy1 ester (CAPE) in the proliferation,collagen synthesis and apoptosis of hepatic stellate cells (HSCs) of rats. 目的观察核因子KB(NFKB)抑制剂咖啡酸苯酯(CAPE)在大鼠肝星状细胞(HSCs)增殖,胶原合成和细胞凋亡方面的作用。
- International Hepatology: Besides the important role of hepatic stellate cell in liver fibrosis development， are there any other important mechanisms involving liver fibrosis development? 国际肝病：除了肝星状细胞在肝纤维化发生中的重要作用，还有哪些机制参与了肝纤维化的发生？
- The activation of hepatic gluconeogenesis plays an important role in maintaining blood glucose level within a narrow range by hormone regulation in the long-term starvation. 肝糖异生作用是长期饥饿下机体维持血糖平衡的主要途径,其主要依靠激素的调节,但不适当的调节可引起糖尿病和其他遗传代谢性疾病。
- In addition, the activity of elastase relates to the progression of hepatic fibrosis. 并且发现,弹性蛋白酶的活性与肝纤维化的进程有关。
