Abstract Thirty-two SPF Wistar rats were randomily devided into four groups (n= 8 each). Control group and EN group were fed rat chow and water ad lib,TPN-Ala-Gln group was fed TPN with 2% Ala-Gln, which was isonitrogenous and isocaloric to TPN group.

• 作者采用SPF大鼠以TPN、TPN液中添加丙氨酰－谷氨酰胺（Ala－Gln）和经肠饮食（EN）三种营养方式支持一周后，造成创伤性休克，观察了大鼠在接受不同营养方式支持一周后，肠道屏障功能对严重创伤应激状态的影响，以及Ala－Gln是否具有维持肠道屏障功能的作用。