AIM: To observe the effect of diethylstilbestrol (DES) on hepatoma 22(H 22 )metastasis in mice and to explore its mechanism.

• 目的 :探讨己烯雌酚 (diethylstilbestrol；DES)对小鼠H2 2 肝癌细胞在小鼠体内造成肺转移的影响及其机制 .