AIM To study the effect of geldanamycin (GDM) on cell cycle of human hepatoma BEL 7402 cells and the antitumor activity of cisplatin and mitomycin C in combination with GDM in vitro and in vivo .

• 目的 研究格尔德霉素 (Geldanamycin ,GDM)对人肝癌BEL 74 0 2细胞周期的影响及顺铂和丝裂霉素C等药物联用GDM后的体外体内抗肿瘤作用。