AGEs amounts of renal cortex was increased markedly and the activity of active form MMP 2 (62KD) reduced significantly in rats neceiving AGE RSP four weeks after treatment as compared with those in rats treated with native RSP or in control.

• 与天然血清组及空白对照组比较 ；注射 AGE- RSP的大鼠肾皮质 AGEs含量明显增加 ；活性形式的 MMP- 2活性明显降低 ( P<0 .；0 5 )；而同时注射 AG的大鼠 MMP- 2活性明显增加 ( P<0