A total of 20 compounds were isolated from the strain F121112 by the column chromatography on silica gel, RP-Cig and Sephadex LH-20, followed by reverse-phase high performance liquid chromatography.

• 采用生物活性跟踪分离的方法,通过硅胶柱层析、ODS C-18柱层析、Sephadex LH-20凝胶层析以及RP-HPLC等各种色谱技术,对F121112产生的生物活性物质进行分离纯化,得到了20个化合物。