A series of 2 pyrazolyl 5 substituted 1,3,4 oxadiazoles were synthesized starting from 5 pyrazole formic acid hydrazide and carboxylic acid by one pot method in the presence of phosphorus oxychloride.

• 以 5 吡唑甲酰肼和取代羧酸为起始物 ；运用“一锅煮”法合成了一系列 2 取代 5 吡唑基 1 ；3 ；4 ?二唑 .