A preliminary study on optical conversion from ethyl 4-chloro-3-oxobutanoate (COBE) to ethyl (R)4-chloro-3-hydroxybutanoate (R-CHBE) wasalso conducted.

• 利用重组的KR进行了4-氯-3-酮基-丁酸乙酯（COBE）手性转化为R-4-氯-3-羟基丁酸乙酯（CHBE）的初步研究。