A method for determination of fleroxacin concentration in plasma by HPLC was established in order to monitor the plasma concentration of fleroxacin and study the pharmacokinetics of human body.

• 建立固相萃取结合HPLC高效液相色谱法对人体血浆中的氟罗沙星含量进行检测,为氟罗沙星的体内血药浓度监测和人体药代动力学研究提供测定方法。