A hybridoma secreting monoclonal antibody (McAb) against human antidiu-retic hormone (ADH) was obtained by fusion of Sp2/0 myeloma cells with spleen cells from BALB/c mice immunized with ADH.

• 应用B淋巴细胞杂交瘤技术,成功地建立了分泌抗抗利尿激素(ADH)的单克隆抗体细胞株。