2 cases of them were abnormal autosomal chromosome, with take up about 10% in abnormal kayotype. 41 cases with primary amenia were normal karyot...

• 41例染色体正常,其中单纯性腺发育不全27例;先天无子宫、无阴道10例;4例患者出现男性化特征。结论染色体异常是导致原发闭经的重要原因之一。